Hemoglobinemia and the Hemoglobinurias

Abstract

BLACKWATER, or more scientifically, hemoglobinuria, attracts the attention of patient and physician as do few other symptoms. Indeed, few other symptoms indicate so serious a disturbance of body processes or carry so grave a prognosis. The diseases producing or associated with hemoglobinuria, with some exceptions, usually either have a high fatality rate or are extremely chronic and disabling.It is the purpose of this paper to review the mechanisms by which hemoglobinuria is produced, to consider its pathologic effects and to summarize the important features of the clinical syndromes that lead to the excretion of hemoglobin in the urine.Pathologic . . .