Viroids and virusoids are related to group I introns.
- 1 September 1986
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 83 (17), 6250-6254
- https://doi.org/10.1073/pnas.83.17.6250
Abstract
Group I introns are found in nuclear rRNA genes, mitochondrial mRNA and rRNA genes, and chloroplast tRNA genes. The hallmarks of this intron class are a 16-nucleotide consensus sequence and three sets of complementary sequences. The viroids (circular pathogenic plant RNAs) and the virusoids (plant satellite RNAs) also contain the consensus sequence and the three sets of complementary bases. Pairing of the complementary bases would generate a viroid structure resembling a group I intron, which might be stablized in vivo through interactions with proteins. The Tetrahymena self-splicing rRNA intron further has sequences homologous with regions of potato spindle tuber viroid associated with the severity of viroid symptoms.Keywords
This publication has 52 references indexed in Scilit:
- Excision-amplification of mitochondrial DNA during senescence in Podospora anserinaJournal of Molecular Biology, 1985
- Splicing of large ribosomal precursor RNA and processing of intron RNA in yeast mitochondriaCell, 1984
- RNA splicing in neurospora mitochondria: Self-splicing of a mitochondrial intron in vitroCell, 1984
- Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage–ligation reactionNature, 1983
- Expression of the split gene cob in yeast: Evidence for a precursor of a “maturase” protein translated from intron 4 and preceding exonsCell, 1982
- Critical sequences within mitochondrial introns: Cis-dominant mutations of the “cytochrome-b-like” intron of the oxidase geneCell, 1982
- Critical sequences within mitochondrial introns: Pleiotropic mRNA maturase and cis-dominant signals of the box intron controlling reductase and oxidaseCell, 1982
- Nucleotide Sequence and Secondary Structure of Citrus Exocortis and Chrysanthemum Stunt ViroidEuropean Journal of Biochemistry, 1982
- A pathway of cytochrome b mRNA processing in yeast mitochondria: Specific splicing steps and an intron-derived circular RNACell, 1980
- Structure and structure formation of viroidsJournal of Molecular Biology, 1979