Osteopontin Stimulates Cell Motility and Nuclear Factor κB-mediated Secretion of Urokinase Type Plasminogen Activator through Phosphatidylinositol 3-Kinase/Akt Signaling Pathways in Breast Cancer Cells
Open Access
- 1 August 2003
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 278 (31), 28593-28606
- https://doi.org/10.1074/jbc.m303445200
Abstract
No abstract availableKeywords
This publication has 49 references indexed in Scilit:
- Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathwaysOncogene, 2003
- Syk, a Protein-tyrosine Kinase, Suppresses the Cell Motility and Nuclear Factor κB-mediated Secretion of Urokinase Type Plasminogen Activator by Inhibiting the Phosphatidylinositol 3′-Kinase Activity in Breast Cancer CellsPublished by Elsevier ,2003
- Phosphatidylinositol 3-Kinase and NF-κB Regulate Motility of Invasive MDA-MB-231 Human Breast Cancer Cells by the Secretion of Urokinase-type Plasminogen ActivatorJournal of Biological Chemistry, 2002
- Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cellsOncogene, 1999
- Altered wound healing in mice lacking a functional osteopontin gene (spp1).JCI Insight, 1998
- Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.JCI Insight, 1997
- uPA, uPAR, PAI-I: Key intersection of proteolytic, adhesive and chemotacfic highways?Immunology Today, 1997
- THE NF-κB AND IκB PROTEINS: New Discoveries and InsightsAnnual Review of Immunology, 1996
- Secreted phosphoprotein mrna is induced during multi‐stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblastsInternational Journal of Cancer, 1990
- A secreted phosphoprotein marker for neoplastic transformation of both epithelial and fibroblastic cellsNature, 1983