TERMINAL BRONCHIOLAR OR "ALVEOLAR CELL" CANCER OF THE LUNG

Abstract
At Memorial Hospital we have noted in the past several years a definite and rapid increase in the incidence of cancer of the lung. At the same time, a corresponding increase in the number of lesions that we classify as "terminal bronchiolar or alveolar cell cancer of the lung" has been reported by the department of pathology. Malassez,1in 1876 was the first to describe the multiple, nodular form of alveolar cell carcinoma. At autopsy both of his patient's lungs were found to be studded with pea-sized nodules, but the bronchi themselves were free of tumor. Microscopic study of the lesion revealed the alveoli to be lined with a cylindrical, cuboidal and flat epithelium. The peribronchial lymph nodes contained metastatic tumors. In 1903 Musser2described a diffuse form of this type of lung cancer. This is a rarer type, which may involve a single lobe or an entire