The solubility of sulphadiazine in water-dimethylformamide mixtures
- 1 November 1968
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 20 (11), 830-835
- https://doi.org/10.1111/j.2042-7158.1968.tb09656.x
Abstract
Precise measurements of the solubility of sulphadiazine in water, dimethylformamide (DMF), and a range of mixtures of these solvents have been made at 20°, 30°, and 40°. The solubility of sulphadiazine in the mixtures increases with their DMF content. The partial molar heats and entropies of solution decrease with increasing DMF concentration.Keywords
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