Differentiation of Mouse Neuroblastoma Cells under Increased Oxygen Tension
- 1 January 1980
- journal article
- research article
- Published by S. Karger AG in Pathobiology
- Vol. 48 (5), 374-380
- https://doi.org/10.1159/000163002
Abstract
After exposure to increased oxygen tension for 3 days, cultured mouse neuroblastoma cells were found to undergo morphological differentiation and to significantly increase their ecto-acetylcholinesterase activity. Differentiation could not be blocked by KCN or lipid-soluble antioxidants, indicating that neither an increased respiration, nor an increased oxidation of membrane lipids was responsible for the effect.Keywords
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