Toxicity of Antiviral Nucleoside Analogs and the Human Mitochondrial DNA Polymerase
Top Cited Papers
Open Access
- 1 November 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (44), 40847-40857
- https://doi.org/10.1074/jbc.m106743200
Abstract
No abstract availableKeywords
This publication has 56 references indexed in Scilit:
- Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cellsJournal of the Neurological Sciences, 1997
- Fialuridine is phosphorylated and inhibits DNA synthesis in isolated rat hepatic mitochondriaAntiviral Research, 1997
- In situ localization of mitochondrial DNA replication in intact mammalian cells.The Journal of cell biology, 1996
- Zidovudine and dideoxynucleosides deplete wild-type mitochondrial DNA levels and increase deleted mitochondrial DNA levels in cultured Kearns-Sayre syndrome fibroblastsBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1996
- AZT Incorporation into Mitochondria: Study in a Human Myeloid Cell LineDNA and Cell Biology, 1996
- Mitochondrial toxicity of antiviral drugsNature Medicine, 1995
- Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesisAntimicrobial Agents and Chemotherapy, 1994
- Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathyThe Lancet, 1991
- Alternating and intermittent regimens of zidovudine (3′-azido-3′-deoxythymidine) and dideoxycytidine (2′,3′-dideoxycytidine) in the treatment of patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complexThe American Journal of Medicine, 1990
- Studies on the inhibition of mitochondrial DNA replication by 3′-azido-3′-dhoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replicationBiochemical Pharmacology, 1989