The Cure of Plasmodium Knowlesi Malaria in Rhesus Monkeys with Sulfanilamide and Their Susceptibility to Reinfection

Abstract

Summary The foregoing experiments demonstrate that sulfanilamide (paramido benzene sulfonamide) acts as a sterilizing agent against P. knowlesi infections in rhesus monkeys. Experimental evidence is presented to show that there remains a residual immunity which is effective to the extent of preventing death of reinoculated monkeys as late as 3 months following eradication of infection.