Drug/Dye‐Loaded, Multifunctional Iron Oxide Nanoparticles for Combined Targeted Cancer Therapy and Dual Optical/Magnetic Resonance Imaging
Top Cited Papers
- 5 August 2009
- Vol. 5 (16), 1862-1868
- https://doi.org/10.1002/smll.200900389
Abstract
A biocompatible, multimodal, and theranostic functional iron oxide nanoparticle is synthesized using a novel water‐based method and exerts excellent properties for targeted cancer therapy, and optical and magnetic resonance imaging. For the first time, a facile, modified solvent diffusion method is used for the co‐encapsulation of both an anticancer drug and near‐infrared dyes. The resulting folate‐derivatized theranostics nanoparticles could allow for targeted optical/magnetic resonance imaging and targeted killing of folate‐expressing cancer cells.Keywords
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