Effects of Antianxiety Drug and Personality on Stress‐Inducing Psychomotor Performance Test
- 3 February 1978
- journal article
- research article
- Published by Wiley in The Journal of Clinical Pharmacology
- Vol. 18 (2-3), 125-130
- https://doi.org/10.1002/j.1552-4604.1978.tb02432.x
Abstract
The effects of an antianxiety drug was studied in relation to personality characteristics on a psychomotor performance test. Healthy women college students (48) were chosen as having either high or low levels of trait anxiety, neuroticism or extroversion. Subjects with high trait anxiety and/or neuroticism tended to show a decrease in both speed and accuracy of the mirror drawing test (MDT) in the initial nondrug trials. Bromazepam, 5 mg, a benzodiazepine derivative, decreased this decrement in highly anxious subjects but worsened the speed in less anxious subjects. The personality traits of subjects and the degree to which a performance test will induce stress, must be considered when evaluating the effects of antianxiety drugs on the performance of normal volunteers. The clinical anxiety-reducing efficacy of drugs may be predicted by using the MDT in subjects with high levels of anxiety and/or neuroticism.This publication has 24 references indexed in Scilit:
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