Intestinal Dipeptide Hydrolase Activities in Undernourished Children
- 1 December 1971
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 46 (250), 801-804
- https://doi.org/10.1136/adc.46.250.801
Abstract
Intestinal dipeptide hydrolase enzymes cleave dipeptides into amino acids. In 8 undernourished children with diarrhoea, mean intestinal mucosal glyclyl-proline hydrolase activity was reduced 40%, valyl-proline hydrolase activity 38%, and alkaline phosphatase activity 54%, as compared with 4 controls. The use of hydrolysed proteins or simple amino acid mixtures in the initial treatment of undernourished children is suggested.Keywords
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