Observations préliminaires sur quelques effets du lactose chez le porc : Complexes myoélectriques de l'intestin grêle, motricité caecale et diarrhée

Abstract

The effects of ingesting a semi-synthetic diet containing 82% pure lactose on the organization of the electrical activities in the small bowel were studied in 5 large white pigs weighing, on an average, 57 kg and fitted with permanent intraparietal supple electrodes. In another pig a reentrant cannula was placed in the distal part of the jejunum to check and evaluate the effect of this diet on the volumes of digesta passing through the gut. The organization of spiking activities in the duodenum was normal. But, the aboral migration of the consecutive phases of the myoelectrical complexes was greatly disturbed. In the jejuno-ileal area regular spiking activities appeared and disappeared in a relatively anarchic manner. An overall decrease in the regular spiking activities and even a total absence of activity in the ileum for periods of at least 5 h and maximum 21 h, was observed. The higher the lactose intake level the longer lasted this effect. Parallel to that the intensity of the irregular spiking activities considerably decreased. Rapid transit of a volume of digesta 2 times larger than with a standard diet and 3-4 times larger volume than with a maize starch diet was seen in the jejunum. These disturbances cannot be easily explained either by an insulin effect or by the only effect of an intestinal repletion like that occurring in other feeding conditions.