Radiofluoride photoscanning of bone for reticulum cell sarcoma. Early detection of bone involvement

Abstract

Radiofluoride bne scanning is shown to be a sensitive means for detecting the bone lesions of reticulum cell sarcoma. This is in contrast to methods of bone photoscanning with radioisotopes of Sr which have failed to detect these lesions. Four patients with reticulum cell sarcoma involving bone were studied with F18 bone scans. All 4 patients were scan positive for the bone lesions which were eventually demonstrated on roentgenograms or at postmortem examination. Concomitantly, X-ray studies of the bone were nondiagnostic in 2 of the patients. In 1 patient, a good clinical response to radiotherapy was correlated with a relative decrease in F18 uptake in the treated area.