Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration
- 8 August 1995
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 50 (4), 571-576
- https://doi.org/10.1016/0006-2952(95)00160-2
Abstract
No abstract availableKeywords
This publication has 5 references indexed in Scilit:
- In vivo stability, disposition and metabolism of a “hybrid” oligonucleotide phosphorothioate in ratsBiochemical Pharmacology, 1995
- Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1Biochemical Pharmacology, 1995
- Pharmacokinetics of Antisense OligonucleotidesClinical Pharmacokinetics, 1995
- Study of antisense oligonucleotide phosphorothioates containing segments of oligodeoxynucleotides and 2′-o- methyloligoribonucleotidesBioorganic & Medicinal Chemistry Letters, 1994
- Pharmacokinetics of an Antisense Phosphorothioate Oligodeoxynucleotide againstrevfrom Human Immunodeficiency Virus Type 1 in the Adult Male Rat Following Single Injections and Continuous InfusionAntisense Research and Development, 1994