Molecular cloning and characterization of cDNA sequences coding for rat relaxin
- 1 May 1981
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 291 (5811), 127-131
- https://doi.org/10.1038/291127a0
Abstract
Using a synthetic oligonucleotide primer, cloned DNA fragments, each containing the entire coding sequence of rat relaxin, were isolated from a clone bank of ovarian mRNA sequences. The nucleotide sequence of these clones demonstrates that relaxin is synthesized as a preprorelaxin molecule with an unexpectedly large connecting peptide of 105 amino acid residues.Keywords
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