HIGHLY EFFICIENT ASYMMETRIC SYNTHESIS OF (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL FROM GLYCEROL
- 5 March 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 13 (3), 401-404
- https://doi.org/10.1246/cl.1984.401
Abstract
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol was prepared from glycerol in high yield with high optical purity by simple procedure. The procedure involves acylation of cyclic tin(IV) alkoxide with an optical active acid chloride in the crucial step.Keywords
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