Entamoeba histolytica-associated diarrheal illness is negatively associated with the growth of preschool children: evidence from a prospective study
- 1 November 2006
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 100 (11), 1032-1038
- https://doi.org/10.1016/j.trstmh.2005.12.012
Abstract
The enteric protozoa, Cryptosporidium, Giardia and Entamoeba histolytica, cause diarrhea in children. We investigated the association of enteric protozoan-associated diarrheal illness with the nutritional status and growth of preschool children in Dhaka, Bangladesh. The subjects were 221 children aged 2-5 years who were followed prospectively for diarrheal illness for 3 years. The weight and height of the children were measured at entry and at 4-month intervals. Cryptosporidium and E. histolytica were diagnosed with commercially available stool antigen detection kits. Giardia was diagnosed by conventional microscopy. Cryptosporidium- and Giardia-associated diarrheal illness was not associated with the growth of the children. Children with E. histolytica-associated diarrheal illness had lower weight for age Z-score changes (-0.103+/-0.120 vs. 0.176+/-0.052, P=0.038). Similarly, the change in height for age Z-score was lower in children with E. histolytica-associated diarrheal illness (-0.348+/-0.186 vs. 0.142+/-0.08, P=0.018). Children with E. histolytica-associated diarrheal illness were 2.93 times (95% CI 1.01-8.52, P=0.047) more likely to be malnourished and 4.69 times (95% CI 1.55-14.18, P=0.006) more prone to be stunted. Entamoeba histolytica-associated diarrheal illness was negatively associated with the growth of preschool children.Keywords
This publication has 22 references indexed in Scilit:
- Prospective evaluation of lactose malabsorption by lactose hydrogen breath test in individuals infected with and passing cystsEntamoeba histolyticaBritish Journal of Nutrition, 2004
- Estimates of Global Prevalence of Childhood Underweight in 1990 and 2015JAMA, 2004
- Diarrhea, respiratory infections, protozoan gastrointestinal parasites, and child growth in Kathmandu, NepalAmerican Journal of Physical Anthropology, 2003
- Innate and Acquired Resistance to Amebiasis in Bangladeshi ChildrenThe Journal of Infectious Diseases, 2002
- Intestinal parasitic infections in young children in São Paulo, Brazil: prevalences, temporal trends and associations with physical growthPathogens and Global Health, 2002
- Asymptomatic and Symptomatic Cryptosporidiosis: Their Acute Effect on Weight Gain in Peruvian ChildrenAmerican Journal of Epidemiology, 1997
- The effect of chronic intestinal parasitic infection on maternal and perinatal outcomeInternational Journal of Gynecology & Obstetrics, 1996
- Ascariasis and childhood malnutritionParasitology, 1993
- ARE DIARRHOEA CONTROL PROGRAMMES LIKELY TO REDUCE CHILDHOOD MALNUTRITION? OBSERVATIONS FROM RURAL BANGLADESHThe Lancet, 1989
- Risk factors for death in complicated diarrhoea of children.BMJ, 1985