The Hfr status of Pseudomonas aeruginosa is stabilized by integrative suppression
- 1 September 1986
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 204 (3), 519-523
- https://doi.org/10.1007/bf00331034
Abstract
A temperature-sensitive mutant (dna-11) with the phenotype of a mutant defective in the initiation of DNA replication, was isolated from an Hfr-like FP2 donor of Pseudomonas aeruginosa. Reversion of its temperature-sensitive character was achieved by integrative suppression rather than by backmutation or an additional suppressor mutation. The dna-11 mutant proved to be helpful in stabilizing the Hfr status of the original host.Keywords
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