Abstract
Several methods for the extraction of pituitary thyrotropic hormone added to normal urine were described; acetone and alcohol-ether methods gave a very satisfactory recovery, as judged by the response of the chick thyroid. Urines from 2 cases of myxedema, 1 case of post-operative hypothyroidism, and 2 acromegalics were tested for thyrotropic activity; 1 case of myxedema gave results suggesting possible thyrotropic activity. Sera from 9 schizophrenic patients did not show any anti-thyrotropic activity when injected into chicks along with known amts. of thyrotropic substance.