Failure to Detect, in Human Sera, Antibodies Cross-Reactive With Group-Specific Antigens of Murine Leukemia Virus

Abstract

The sera of 25 adult cancer patients and controls, 52 children with various neoplasms, 20 juvenile patients with connective tissue disorders, and 31 healthy laboratory workers potentially exposed to RNA tumor viruses were screened in sensitive radioimmunoassays for antibodies cross-reacting with highly purified group-specific antigen of murine leukemia virus (p30). No antibody activity was detected.