NEUROPSYCHOLOGICAL ASPECTS OF TUBEROUS SCLEROSIS IN RELATION TO EPILEPSY AND MRI FINDINGS
- 1 August 1991
- journal article
- Published by Wiley in Developmental Medicine and Child Neurology
- Vol. 33 (8), 698-705
- https://doi.org/10.1111/j.1469-8749.1991.tb14947.x
Abstract
The neuropsychological performances, outcome of epilepsy and MRI topography of tubers of 23 children with tuberous sclerosis were reviewed. Seven children had normal intelligence, 10 had mental retardation, and six mental retardation and autism. An adverse association was found between the number of lesions and IQ, behaviour and severity of epilepsy. Posterior lesions, in addition to frontal-lobe dysfunction, were observed in children with autism. Tuberous sclerosis with well-defined cerebral lesions may represent a model for the relationship between different neuropsychiatric problems.Keywords
This publication has 20 references indexed in Scilit:
- Topographic Comparative Study of Magnetic Resonance Imaging and Electroencephalography in 34 Children with Tuberous SclerosisEpilepsia, 1990
- Magnetic Resonance Imaging in Autism: Preliminary ReportNeuropediatrics, 1989
- Is autism associated with anomalous dominance?Journal of Autism and Developmental Disorders, 1988
- Hypoplasia of Cerebellar Vermal Lobules VI and VII in AutismNew England Journal of Medicine, 1988
- Autism and Infantile Spasms in Children with Tuberous SclerosisDevelopmental Medicine and Child Neurology, 1987
- PSYCHIATRIC DISORDER AMONG CHILDREN WITH TUBEROUS SCLEROSISDevelopmental Medicine and Child Neurology, 1987
- Tuberous sclerosis, early onset of seizures, and mental subnormalityNeurology, 1982
- The Long-term Effects of Prefrontal LeukotomyArchives of Neurology, 1981
- Computerized Tomographic Scan Findings in Patients With Autistic BehaviorArchives of Neurology, 1980
- A Neurological Model for Childhood AutismArchives of Neurology, 1978