Aortic compliance in connective tissue disorders affecting the eye

Abstract

Several connective tissue diseases are characterized by specific ocular changes. When these diseases affect the aortic wall as in Marfan syndrome, Ehlers-Danlos syndrome and homocystinuria, abnormal aortic compliance measurements enable us to make a diagnosis, even in a mildly affected individual, which allows for early and frequent ophthalmological assessment to minimize the effect of ocular manifestations.