Stilbestrol-Induced Porphyria: Increase in Hepatic δ-Aminolevulinic Acid Synthetase
Open Access
- 1 October 1966
- journal article
- research article
- Published by American Society of Hematology in Blood
- Vol. 28 (4), 569-572
- https://doi.org/10.1182/blood.v28.4.569.569
Abstract
An increase in hepatic δ-aminolevulinic acid synthetase is demonstrated in a patient with cutaneous porphyria induced by stilbestrol. A genetically determined increase in this rate-limiting enzyme appears to be the basic abnormality in all of the hepatic porphyrias.Keywords
This publication has 9 references indexed in Scilit:
- INDUCTION IN VITRO OF SYNTHESIS OF DELTA-AMINOLEVULINIC ACID SYNTHETASE IN CHEMICAL PORPHYRIA - A RESPONSE TO CERTAIN DRUGS SEX HORMONES AND FOREIGN CHEMICALS1966
- Porphyria cutanea tarda induced by estrogensArchives of Dermatology, 1965
- ACUTE INTERMITTENT PORPHYRIA: THE FIRST “OVERPRODUCTION DISEASE” LOCALIZED TO A SPECIFIC ENZYMEProceedings of the National Academy of Sciences, 1965
- HEPATIC PORPHYRIA AND DRUG‐INDUCED OR CHEMICAL PORPHYRIA*Annals of the New York Academy of Sciences, 1965
- A SUGGESTED CONTROL GENE MECHANISM FOR THE EXCESSIVE PRODUCTION OF TYPES I AND III PORPHYRINS IN CONGENITAL ERYTHROPOIETIC PORPHYRIAProceedings of the National Academy of Sciences, 1964
- A study of the urinary porphyrins and porphyrin precursors in patients with malignant disease receiving diethylstilbestrolMetabolism, 1964
- Factors affecting the excretion of porphyrin precursors by patients with acute intermittent porphyria. II. The effect of ethinyl estradiolMetabolism, 1964
- Increase in Activity of δ-Aminolevulinic Acid Synthetase in Liver Mitochondria Induced by Feeding of 3, 5-Dicarbethoxy-1, 4-dihydrocollidineJournal of Biological Chemistry, 1963
- OCCURRENCE AND DETERMINATION OF DELTA-AMINOLEVULINIC ACID AND PORPHOBILINOGEN IN URINE1956