Expression of protein kinase C subspecies in rat retina
- 14 September 1992
- journal article
- Published by Wiley in FEBS Letters
- Vol. 309 (3), 409-412
- https://doi.org/10.1016/0014-5793(92)80818-2
Abstract
An extract of rat retina was subjected to Mono Q followed by chromatography on hydroxyapatite, and the protein kinase C (PKC) subspecies were identified by immunobiol and biochemical analysis. It was found that, although the relative activities assayed with myelin basic protein as a common phosphate acceptor vary greatly with one another, the α-, βI-, βII-, γ-, δ-, ε-, ξ-, and another structurally unknown PKC subspecies are expressed in this tissue. Thus, the retina is a unique tissue which expresses most of the PKC subspecies so far identified in mammals.Keywords
This publication has 15 references indexed in Scilit:
- Isolation and characterization of the epsilon subspecies of protein kinase C from rat brain.Proceedings of the National Academy of Sciences, 1992
- The occurrence of three isoenzymes of protein kinase C (α, β and γ) in retinas of different speciesBrain Research, 1992
- Differential localization of protein kinase C isozymes in retinal neurons.The Journal of cell biology, 1991
- [37] Preparation and use of protein kinase C subspecies-specific anti-peptide antibodies for immunostainingMethods in Enzymology, 1991
- Subspecies of arrestin from bovine retinaEuropean Journal of Biochemistry, 1990
- Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties.Proceedings of the National Academy of Sciences, 1989
- Isolation and characterization of two new Drosophila protein kinase C genes, including one specifically expressed in photoreceptor cellsCell, 1989
- The molecular heterogeneity of protein kinase C and its implications for cellular regulationNature, 1988
- Identification of the structures of multiple subspecies of protein kinase C expressed in rat brainFEBS Letters, 1987
- Isozymic forms of rat brain Ca2+-activated and phospholipid-dependent protein kinase.Proceedings of the National Academy of Sciences, 1986