Role of Viral Glycoproteins in Haemolysis by Influenza B Virus
- 1 March 1982
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 59 (1), 183-186
- https://doi.org/10.1099/0022-1317-59-1-183
Abstract
Summary Influenza B virus exhibited haemolytic activity at low pH, but the pH profile for its activity varied from strain to strain. The results of selective heat-inactivation of the enzyme activity of neuraminidase (NA) or elimination from virions of the enzyme-active portion of the NA molecule by trypsin digestion, suggest that proteolytically cleaved haemagglutinin, but not enzyme activity of NA, is essential for haemolysis by influenza B virus.Keywords
This publication has 6 references indexed in Scilit:
- Influenza viruses cause hemolysis and fusion of cellsVirology, 1981
- pH-dependent hemolysis by influenza, Semliki Forest virus, and Sendai virusVirology, 1981
- The function of the neuraminidase in membrane fusion induced by myxovirusesVirology, 1980
- Specific inhibition of paramyxovirus and myxovirus replication by oligopeptides with amino acid sequences similar to those at the N-termini of the Fl or HA2 viral polypeptidesVirology, 1980
- Fusion between cell membrane and liposomes containing the glycoproteins of influenza virusVirology, 1980
- Activation of precursors to both glycoproteins of Newcastle disease virus by proteolytic cleavageVirology, 1977