Experimental cutaneous leishmaniasis. IV. Selective suppression of cell-mediated immunity during the response of guinea-pigs to infection with Leishmania enriettii.
- 1 February 1974
- journal article
- Vol. 16 (2), 189-202
Abstract
The purpose of this study was to determine whether suppression of acquired, cell-mediated immunity occurred during the course of cutaneous leishmaniasis of the guinea-pig. In order to do this, groups of animals were infected with amastigotes of Leishmania enriettii in doses ranging from 101 to 2 × 108 organisms. The clinical course of primary and metastatic infection was followed for up to 30 weeks and the immunological response was examined by skin tests of hypersensitivity to soluble leishmanial antigens, by detection of circulating antibody, and by determining the resistance of animals to reinfection with fresh organisms.This publication has 12 references indexed in Scilit:
- Experimental cutaneous leishmaniasis. II. Effects of immunosuppression and antigenic competition on the course of infection with Leishmania enriettii in the guinea-pig.1972
- Experimental cutaneous leishmaniasis. 3. Effects of thymectomy on the course of infection of CBA mice with Leishmania tropica.1972
- Immunological aspects of clinical leishmaniasis.1970
- Immunity in cutaneous leishmaniasis of the guinea-pig.1970
- IMMUNITY IN SCHISTOSOMIASISAnnals of the New York Academy of Sciences, 1969
- Immunity to protozoal infections.1969
- Problems in Leishmaniasis Related to ImmunologyPublished by Springer Nature ,1969
- Cellular hypersensitivity and cellular immunity in the pathogensis of tuberculosis: specificity, systemic and local nature, and associated macrophage enzymes.1968
- Studies on the immunology and serology of Leishmaniasis V. The use of particles as vehicles in passive agglutination testsTransactions of the Royal Society of Tropical Medicine and Hygiene, 1967
- LeishmaniaAdvances in Parasitology, 1964