Separation of Cellular from Extracellular Controls of Drinking in Rats by Frontal Brain Damage
- 27 December 1968
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 162 (3861), 1501-1503
- https://doi.org/10.1126/science.162.3861.1501
Abstract
Rats that had undergone removal of the frontal portion of the brain, including the olfactory bulbs, did not drink, or drank less than controls, when subjected to cellular dehydration. These same animals drank normally in response to extracellular volume reduction. Rats from which only the olfactory bulbs had been removed drank normally in both tests. An essential part of the neurological system mediating drinking produced by cellular dehydration, but not by volume reduction, therefore lies within the frontal cortex or immediate subcortical tissue.Keywords
This publication has 13 references indexed in Scilit:
- Cellular Dehydration and Hypovolaemia are Additive in producing ThirstNature, 1968
- Additivity of stimuli for drinking in rats.Journal of Comparative and Physiological Psychology, 1968
- Sodium thirst in nephrectomized and nephrectomized-anosmic ratsPsychonomic Science, 1967
- Water intake of hyposalemic anosmic ratsPsychonomic Science, 1967
- The Effect of Hypovolemia on Drinking in Rats With Lateral Hypothalamic Damage.Experimental Biology and Medicine, 1967
- Exaggerated Prandial Drinking in the Rat without Salivary GlandsNature, 1964
- Oral and postingestional determinants of the intake of various solutions in rats with esophageal fistulas.Journal of Comparative and Physiological Psychology, 1963
- Drinking by rats depleted of body fluid without increase in osmotic pressureThe Journal of Physiology, 1961
- Production of Polydipsia in Normal Rats by an Intermittent Food ScheduleScience, 1961
- Some Characteristics of the Hypothalamic “Drinking Centre” in the Goat as Shown by the Use of Permanent ElectrodesActa Physiologica Scandinavica, 1960