Role of Telomerase in Normal and Cancer Cells
- 1 July 2000
- journal article
- review article
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 18 (13), 2626-2634
- https://doi.org/10.1200/jco.2000.18.13.2626
Abstract
Shortening of the telomeric DNA at chromosome ends is postulated to limit the lifespan of human cells. In contrast, activation of telomerase, the enzyme that synthesizes telomeric DNA, is...Keywords
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