Studies on a case of actinomycetoma pedis in Queensland; I

Abstract

An Actinomycete isolated in pure culture on 5 occasions from a human case of mycetoma pedis was found to resemble Nocardia madurae (Vincent) Blanchard. The organism formed chains of conidia and also sclerotic bodies inside which clusters of coiled conidial chains were found. It developed red pigment and a specific smell and was not pathogenic or only weakly so to laboratory animals, although local ray-fungus-like lesions were produced after repeated injections. They remained for only a short period and healed without further complications. The organism was sensitive to several antibiotics but when freshly isolated was resistant to penicillin.