Long-Lived Species in Irradiated N 2 O-Flushed Saline Phosphate Buffer, with Toxic Effect upon E. coli K-12
- 1 May 1976
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 66 (2), 215-230
- https://doi.org/10.2307/3574392
Abstract
The yield of inactivation of radioresistant strains of Escherichia coli K-12 (wild type and uvr A mutant) suspended in phosphate-buffered saline (PBS) is higher in suspensions irradiated under N2O-bubbling than in suspensions irradiated under N2-bubbling. This sensitization is largely a result of OH-induced toxic products formed in N2O-saturated PBS. Special emphasis is placed on establishing the conditions under which extracellular toxic products with lifetimes exceeding about 20 s are formed. Cl atoms are apparently precursors for these toxic products and N2O and phosphate may potentiate their formation.This publication has 5 references indexed in Scilit:
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