Immunocytochemical detection of ricin. I. Preliminary immunofluorescence studies
- 1 August 1985
- journal article
- research article
- Published by Springer Nature in Journal of Molecular Histology
- Vol. 17 (8), 859-866
- https://doi.org/10.1007/bf01004181
Abstract
Ricin injected into rat musclein vivo can be localized within a few hors using routine immunofluorescence techniques on formalin-fixed tissues. However, the level of sensitivity decreases with increase in size of animal injected, time after administration and decrease in dose given. These findings are discussed in relation to the known chemistry and subcellular mode of action of ricin.This publication has 23 references indexed in Scilit:
- Radioimmunoassays of abrin and ricin in bloodJournal of Toxicology and Environmental Health, 1981
- Toxicity of abrin and ricin in mice and dogsJournal of Toxicology and Environmental Health, 1979
- Mechanism of action of the toxic lectins abrin and ricinNature, 1974
- Ricin: The toxic protein of castor oil seedsToxicology, 1974
- Treatment of abrin and ricin with β‐mercaptoethanol. Opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell‐free systemFEBS Letters, 1972
- Inhibition of Peptide Chain ElongationNature, 1972
- Purification of galactose-binding phytoagglutinins and phytotoxin by affinity column chromatography using sepharoseCellular and Molecular Life Sciences, 1972
- Abrin and Ricin: New Anti-tumour SubstancesNature, 1970
- Antigenicity: Some Molecular AspectsScience, 1969
- Demonstration of Leptospiral and Viral Antigens in Formalin-fixed TissuesNature, 1963