Interaction of Carbamates and Their N-Methylol Derivatives with Cotton and Sephadex, Measured by Gel Filtration

Abstract

During gel filtration from cotton or Sephadex columns, there was, with only one exception, an increase in sorption as the molecular weight of an unsubstituted n-alkyl carbamate was increased by the addition of methylene groups. When a given carbamate was converted to its monomcthylol derivative, sorption decreased progressively. The addition of the first formaldehyde molecule produced a more pronounced effect than did the addition of the second.