Phagocytosis of chromium during patellar osteoarthritic remodelling associated with a knee prosthesis
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Virchows Archiv
- Vol. 382 (1), 119-126
- https://doi.org/10.1007/bf01102746
Abstract
The report is of an anatomico-pathological and electron probe microanalyzer study of a patella with osteoarthritic remodelling, that had been in contact with a cast cobalt-chromium-molybdenum prosthesis for two years and seven months. Abrasion of the metal resulted in preferential phagocytosis of chromium, principally in the wall of an osteoarthritis cyst. This observation indicates that a substance administered by intra-articular pathway for the treatment of osteoarthritis can become phagocytosed, and quite deeply, in the remodelled bone.Keywords
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