THE EFFECT OF POSTURE (STANDING) ON THE SERUM PROTEIN CONCENTRATION AND COLLOID OSMOTIC PRESSURE OF BLOOD FROM THE FOOT IN RELATION TO THE FORMATION OF EDEMA
Open Access
- 1 May 1934
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 13 (3), 447-459
- https://doi.org/10.1172/jci100597
Abstract
Standing at an angle of 75[degree] for about 1 hr. increased serum protein concn. 18-40% and colloid osmotic pressure 29-65% in the blood in the foot of normal subjects. These increases were approximately twice as great as occurred in the blood in the arm. The volume of the leg increased from 3.11 to 4.87 cc. per 100 cc. of leg, but pitting edema did not occur in any of the strictly normal subjects. Patients with chronic (nutritional) edema showed essentially similar changes. Calculations based on the data suggest that an increase in tissue pressure was 3-5 times as important in limiting the loss of fluid from the blood as was the increase in colloid osmotic pressure.This publication has 6 references indexed in Scilit:
- THE EFFECTS OF TEMPERATURE AND OF TISSUE PRESSURE ON THE MOVEMENT OF FLUID THROUGH THE HUMAN CAPILLARY WALLJournal of Clinical Investigation, 1933
- THE PASSAGE OF FLUID AND PROTEIN THROUGH THE HUMAN CAPILLARY WALL DURING VENOUS CONGESTIONJournal of Clinical Investigation, 1932
- THE MOVEMENT OF FLUID THROUGH THE HUMAN CAPILLARY WALL IN RELATION TO VENOUS PRESSURE AND TO THE COLLOID OSMOTIC PRESSURE OF THE BLOODJournal of Clinical Investigation, 1932
- The effects of posture on the circulating blood volumeThe Journal of Physiology, 1931
- On the influence of posture on kidney functionThe Journal of Physiology, 1931
- THE EFFECT OF POSTURE UPON THE COMPOSITION AND VOLUME OF THE BLOOD IN MAN 1Journal of Clinical Investigation, 1928