Methylglyoxal als Abbauprodukt der Glykose.

Abstract

In a mixture of minced muscle and pancreas, methylglyoxal was formed from hexosephosphate but not from glycogen or glucose. The methylglyoxal formed under the influence of the glycolytic ferment in the muscle can not be demonstrated in the absence of pancreas, for the glyoxalase also present in muscle causes rapid conversion to lactic acid. If this latter process is hindered by the addition of pancreas containing antiglyoxalase, the formation of methylglyoxal can be detected. The demonstration of the intermediary formation of methylglyoxal in the decomposition of carbohydrate justifies the assumption that oxidation proceeds from this point.