Platelet Reactivity in Depressed Patients Treated With Paroxetine
Open Access
- 1 September 2000
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 57 (9), 875-882
- https://doi.org/10.1001/archpsyc.57.9.875
Abstract
IN COMMUNITY studies, major depression is a major cause of emotional dysfunction, absenteeism, diminished productivity, and self-reported physical impairment.1-6 Moreover, several studies have revealed that patients with depressive symptoms are at increased risk for developing ischemic heart disease (IHD)7-13 and cerebrovascular disease,14 although some recent reports differ.15,16 Indeed, of patients with IHD, 16% to 23% exhibit symptoms of major depression,17-20 with the presence of depression predictive of future cardiac complications9,17,21 and diminishing survival time.19,22,23Keywords
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