Effect of Citrovorum Factor upon Tyrosine Metabolism in Clinical Scurvy.
- 1 October 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 81 (1), 62-64
- https://doi.org/10.3181/00379727-81-19777
Abstract
A patient with scurvy excreted large quantities of tyrosyl derivatives when given 10 g. of L-tyrosine orally daily. The excretion was not decreased by intramusc. admn. of 6 mg. of citrovorum factor (CF) daily for 5 days, but was promptly corrected by 1 g. of ascorbic acid orally per day. In the doses indicated, CF did not alter the abnormal capillary fragility in this patient nor in another scorbutic patient who received 1 mg. of CF intramusc. daily for 10 days.Keywords
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