BRONCHOGENIC CARCINOMA—A CLINICAL-PATHOLOGICAL STUDY OF 36 AUTOPSIED CASES SEEN AT THE BROOKLYN CANCER INSTITUTE BETWEEN 1937 AND 1945, INCLUSIVE

Abstract

Because of the marked increase in the incidence of diagnosed bronchogenic carcinoma and because of the possibility of cure by pneumonectomy, the earliest possible diagnosis is essential. 444 autopsies were performed at the Brooklyn Cancer Institute between 1937 and 1945. Bronchogenic carcinoma was found in 9%. Of these 88% occurred in [male][male], most commonly between 50 and 60 yrs. of age. The pathologic changes, accounting for the physical and radiographic findings that appear secondary to bronchial occlusion by the growing tumor, are described. The frequent presence of fever, leukocytosis and anemia, indicative of suppurative lung disease distal to the point of bronchial obstruction, is noted. The most thorough investigation, including careful roentgen study and bronchoscopy, is urged for all, especially [male][male] between the ages of 40 and 70 who develop suggestive symptoms[long dash]cough, hemoptysis, chest pain, wt. loss, repeated respiratory infections, low back pain, etc. Cure is dependent upon superior thoracic surgery and early diagnosis. For the non-resectable case, early radiation therapy in maximal dosage gives frequent symptomatic relief and an avg. increase of 6 mos. in life expectancy.