Laminar origin of cortical neurons which project upon the caudate nucleus: A horseradish peroxidase investigation in the cat
- 10 February 1982
- journal article
- research article
- Published by Wiley in Journal of Comparative Neurology
- Vol. 205 (1), 8-29
- https://doi.org/10.1002/cne.902050103
Abstract
The horseradish peroxidase method was used to study the cortical projections upon the caudate nucleus in the cat. The cells of origin of the corticostriatal projection arise from both the supragranular (II and III) and infragranular (V and VI) cortical layers, in contrast to all other known corticofugal pathways to subcortical structures, which appear to arise only from the infragranular layers. This finding has been verified in the present study by several novel surgical procedures, which include direct injections into the caudate nucleus, after the overlying tissues have been removed. The present study also shows that there is a truly widespread distribution of the cells contributing to the corticostriatal projection. Some portion of every neocortical gyrus contains labeled cells, though their relative numbers vary greatly. Also, simple topographical relationships are maintained, but there is much overlap. In addition, present findings show that the corticostriatal projection is strikingly bilateral and originates from regions which are homotopic to the ipsilateral projection.This publication has 77 references indexed in Scilit:
- Corticopontine visual projections in macaque monkeysJournal of Comparative Neurology, 1980
- Projections to the neostriatum from the cat precruciate cortex. Anatomy and physiologyBrain Research, 1979
- Projections from cortex to tectum in the tree shrew,Tupaia glisJournal of Comparative Neurology, 1979
- Connections of striate cortex in the prosimian,galago senegalensisJournal of Comparative Neurology, 1978
- Limbic projections to the cat thalamusCells Tissues Organs, 1978
- Efferent connections of cortical, area 8 (frontal eye field) in Macaca fascicularis. A reinvestigation using the autoradiographic techniqueJournal of Comparative Neurology, 1977
- The organization and postnatal development of the commissural projection of the rat somatic sensory cortexJournal of Comparative Neurology, 1976
- Cortical cells projecting to the dorsal column nuclei of cats. An anatomical study with the horseradish peroxidase techniqueJournal of Comparative Neurology, 1976
- Distribution and properties of commissural and other neurons in cat sensorimotor cortexJournal of Comparative Neurology, 1975
- Structure and relations of limbic cortex and anterior thalamic nuclei in rabbit and catJournal of Comparative Neurology, 1948