Ranitidine in Reflux Oesophagitis

Abstract
The effect of ranitidine on patients with symptomatic esophageal reflux was assessed. In a double-blind comparative trial in 46 patients, a twice daily dose of 150 mg ranitidine was compared with placebo. Relief of pain, endoscopic healing and histological improvement were signficantly better in those treated with ranitidine. Thus, ranitidine is of value in the management of patients with reflux esophagitis and may prevent the development of peptic stricture.