Mitochondria and the Bcl-2 family proteins in apoptosis signaling pathways
- 1 January 2004
- journal article
- Published by Springer Nature in Molecular and Cellular Biochemistry
- Vol. 256 (1/2), 141-155
- https://doi.org/10.1023/b:mcbi.0000009865.70898.36
Abstract
Two main intracellular apoptosis cascades, the receptor and the mitochondria pathway, have been identified. The mitochondrial pathway is controlled by the Bcl-2 proteins. This protein family contains...Keywords
This publication has 97 references indexed in Scilit:
- Preservation of Mitochondrial Structure and Function after Bid- or Bax-Mediated Cytochrome c ReleaseThe Journal of cell biology, 2000
- The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal FragmentJournal of Biological Chemistry, 2000
- Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of ApoptosisScience, 1998
- Movement of Bax from the Cytosol to Mitochondria during ApoptosisThe Journal of cell biology, 1997
- Inhibition of Bax Channel-Forming Activity by Bcl-2Science, 1997
- Bcl-xL forms an ion channel in synthetic lipid membranesNature, 1997
- Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome cCell, 1996
- A Peptide Sequence from Bax That Converts Bcl-2 into an Activator of ApoptosisPublished by Elsevier ,1996
- Primers for Mitochondrial DNA Replication Generated by Endonuclease GScience, 1993
- Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell deathCell, 1993