Spherocytic Hemolytic Anemia and Acute Cholecystitis Caused by Clostridium Welchii

Abstract
SPHEROCYTOSIS with severe intravascular hemolysis, hemoglobinemia and hemoglobinuria associated with Clostridium welchii postabortal septicemia has often been documented.1 2 3 4 5 6 A detailed review of the literature fails to reveal that hemolytic anemia due to C. welchii has been described in acute cholecystitis, in acute gaseous cholecystitis or in infections complicating gallbladder surgery. This paper reports a case of acquired spherocytic hemolytic anemia recently observed in an elderly woman with acute cholecystitis and with C. welchii septicemia.Case ReportA 75-year-old Irish woman (B.C.H. 1780647) entered the hospital on August 23, 1962, because of continuous nonradiating epigastric pain associated with anorexia, nausea, vomiting . . .