Genetic Mapping of a Locus for Triosephosphate Isomerase on the Genome of Escherichia coli K 12

Abstract

SUMMARY: A gene specifying triosephosphate isomerase (tpi) has been located between rha and glpK on the Escherichia coli chromosome. Very recently a gene specifying fructose-6-phosphate kinase (pfk) has been located in this same area and we have found that the tpi and pfk are highly cotransducible. This finding provides the first indication of any close chromosomal association between genes specifying glycolytic enzymes.