CHARACTERIZATION OF VIRUS‐LIKE PARTICLES FROM A PSORIATIC PATIENT WITH RESPECT TO THE POSSIBLE PRESENCE OF PARTICLE‐ASSOCIATED RNA AND RNA‐DIRECTED DNA POLYMERASE
- 1 September 1983
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Series B: Microbiology
- Vol. 91B (1-6), 413-417
- https://doi.org/10.1111/j.1699-0463.1983.tb00069.x
Abstract
Subcellular particles resembling retroviruses with respect to their morphology, density and protein composition, and which were present in the urine of a psoriatic patient were analyzed for the presence of high-MW polyadenylated RNA and RNA-directed DNA polymerase activity. Neither RNA-directed DNA polymerase activity nor high-MW polyadenylated RNA was detected in preparations containing the purified virus-like particles. This was the case even when the amount of particles analyzed exceeded by a factor of .gtoreq. 50 the amount of avian myeloblastosis virus in which polymerase activity and RNA were detected.Keywords
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