The Teratogenic Profile of Sodium Arsenate in the Golden Hamster

Abstract

The spectrum of developmental malformations resulting from the injection of dibasic sodium arsenate into pregnant golden hamsters varies with the time of injection during the critical stages of embryogenesis. However, the spectrum reveals a group of malformations, including anencephaly, renal agenesis, and rib malformations which are quite different from the spectrum of developmental anomalies induced by other teratogenic agents, including certain heavy metals.