Neurophysin Biosynthesis: Conversion of a Putative Precursor During Axonal Transport
- 25 March 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 195 (4284), 1354-1356
- https://doi.org/10.1126/science.65791
Abstract
[35S]Cysteine injected adjacent to the supraoptic nucleus of the rat is rapidly incorporated into a 20,000-dalton protein that, in time, is converted to a 12,000-dalton labeled protein, neurophysin. This putative precursor of neurophysin appears to be synthesized in the supraoptic nucleus and transformed to neurophysin and related peptides during axonal transport to the neurohypophysis.Keywords
This publication has 15 references indexed in Scilit:
- Biosynthesis and axonal transport of rat neurohypophysial proteins and peptides.The Journal of cell biology, 1977
- AXONAL TRANSPORT AND TURNOVER OF NEUROHYPOPHYSEAL PROTEINS IN THE RATAnnals of the New York Academy of Sciences, 1975
- GUINEA PIG NEUROPHYSIN: ISOLATION, DEVELOPMENTAL ASPECTS, BIOSYNTHESIS IN ORGAN CULTUREAnnals of the New York Academy of Sciences, 1975
- THE ROLE OF NEUROPHYSIN PROTEINS: SUGGESTIONS FROM THE STUDY OF THEIR TRANSPORT AND TURNOVER*Annals of the New York Academy of Sciences, 1975
- CONFORMATIONAL EFFECTS ASSOCIATED WITH THE INTERACTION OF POLYPEPTIDE LIGANDS WITH NEUROPHYSINSAnnals of the New York Academy of Sciences, 1975
- Isolated removal of hypothalamic or other brain nuclei of the ratBrain Research, 1973
- ULTRASTRUCTURAL PRESERVATION OF THE DENSE CORE OF POSTERIOR PITUITARY NEUROSECRETORY GRANULES AND ITS IMPLICATIONS FOR HORMONE RELEASEJournal of Endocrinology, 1973
- CHANGES IN THE APPEARANCE OF HYPOTHALAMO-NEUROHYPOPHYSIAL NEUROSECRETORY GRANULES ASSOCIATED WITH THEIR MATURATIONJournal of Endocrinology, 1973
- AXONAL TRANSPORT OF PROTEINS IN THE HYPOTHALAMO‐NEUROHYPOPHYSIAL SYSTEM OF THE RATJournal of Neurochemistry, 1971
- STUDIES ON THE INTRACELLULAR DISTRIBUTION OF VASOPRESSIN*Journal of Neurochemistry, 1963