Synthese von Dekapeptid-Derivaten der Insulinsequenz B21-30

Abstract
Three fully protected derivatives of the decapeptide of insulin B-chain B21-30 have been synthesized by condensation of tripeptides B21-23 with heptapeptide derivatives B24-30. The peptides were synthesized either by stepwise chain elongation using N-hydroxysuccinimide esters or by fragment condensation.