MRI T2 shortening (‘black T2’) in multiple sclerosis
- 1 January 2000
- journal article
- clinical trial
- Published by Wolters Kluwer Health in NeuroReport
- Vol. 11 (1), 15-21
- https://doi.org/10.1097/00001756-200001170-00004
Abstract
Abnormal iron deposition occurs in the brains of patients with multiple sclerosis (MS) and may cause MRI T2 shortening (‘black T2'; BT2). The frequency, distribution and clinical significance of BT2 in MS is unknown. Analysis of brain MRI scans of 114 MS patients showed BT2 in thalamus (n = 65; 57%), putamen (n = 48; 42%), caudate (n = 27; 24%) and Rolandic cortex (n = 9; 8%). BT2 was significantly related to longer disease duration and advancing neurological disability. Wheelchair-bound patients had worse BT2 in thalamus (pKeywords
This publication has 5 references indexed in Scilit:
- MRI in multiple sclerosis: correlation with expanded disability status scale (EDSS)Multiple Sclerosis Journal, 1999
- MRI in chronic toluene abuse: low signal in the cerebral cortex on T2-weighted imagesNeuroradiology, 1998
- Multiple SclerosisArchives of Internal Medicine, 1998
- Are magnetic resonance findings predictive of clinical outcome in therapeutic trials in multiple sclerosis? The dilemma of interferon‐βAnnals of Neurology, 1994
- Rating neurologic impairment in multiple sclerosisNeurology, 1983