Physico-Chemical Studies of (1-Methyl-2-Pyrrolidyl) Methyl Benzilate Methyl Methosulphate: Part I. The Determination of (1-Methyl-2-Pyrrolidyl) Methyl Benzilate Methyl Methosulphate in the Presence of its Breakdown Products
- 1 December 1960
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 12 (Supplement), 171T-175T
- https://doi.org/10.1111/j.2042-7158.1960.tb10472.x
Abstract
The determination of (1-methyl-2-pyrrolidyl)methyl benzilate methyl methosulphate by the formation of a chloroform-soluble, blue complex with ammonium cobaltothiocyanate is described. The optical density in chloroform at 322 mμ is directly related to the amount of compound present. The method is applicable in the presence of breakdown products and has been used to determine the concentration of (methyl-2-pyrrolidyl)methyl benzilate methyl methosulphate in tablets and in linctuses.Keywords
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