Chaetoglobosins, cytotoxic 10-(indol-3-yl)-(13)cytochalasans from Chaetomium spp. I. Production, isolation and some cytological effects of chaetoglobosins A-J.

Abstract
Bioproduction of chaetoglobosins, novel type cytochalasans, by Chaetomium spp. was examined. Details of the culture conditions and methods for separation of the metabolites of C. globosum were presented. Some cytological effects [on human cervical carcinoma HeLa cells, rat muscle cells and mammalian cells] of chaetoglobosins were mentioned.